Block copolymerization forms pH-degradable nanogels that selectively stimulate macrophages, indicating promising immunotherapy.
Living Ring-opening methathesis block copolymerization of oxanorbornenes provides access to pH-degradable nanogels with covalently linked TLR 7/8 agonists, showing selective uptake and immunostimulation of macrophages only for the intact nanogels.
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Kockelmann et al. (2025) studied this question.
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