Study examines lymphatic system structure and function in kidneys of patients with benign cholestasis, suggesting links to venous insufficiency.
The morphology of the lymphatic system of the kidneys in norm and in benign cholestasis on cadaveric material (80 cases) and the functional state of the lymphatic system of the kidneys in 116 patients with benign cholestasis were studied. The structure of the superficial and deep network of lymphatic vessels of the kidneys was studied. The location of the plexuses of lymphatic capillaries along the vascular-nerve bundles inside the renal parenchyma is specified. The renal lymphatic vessels repeat the architecture of arterial and venous vessels, reach the capsule of the nephron, but are absent in the renal glomeruli. It has been revealed that the causes of impaired lymph drainage from the kidneys are a decrease in the contractile function of the valves of the lymphatic vessels, compression of the lumen of the lymphatic collectors, changes in the pressure gradient and disorders of the contractile function of smooth muscle fibers. Morphological and functional disorders of lymph circulation develop in the kidneys in the case of venous congestion in the portal or inferior vena cava and depend on the degree of compensation of venous insufficiency and on the section of the renal parenchyma.
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Кашаева et al. (2025) studied this question.
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