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August 19, 2025Frontiers in MicrobiologyOpen Access

Epidemiology and outcomes of Carbapenem-resistant Enterobacterales infection in high-risk patients in Saudi Arabia

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Retrospective cohort study reveals increased mortality in SOT and BMT recipients with CRE infections, suggesting heightened risks.

Patients with CRE infections from hematological malignancies faced a higher risk of 90-day mortality, indicating severe outcomes in these populations.
Among 155 patients, 37 had hematological malignancies, and those with bla OXA-48 gene infections had a mortality risk nearly four times higher than those with bla NDM gene infections.
Retrospective cohort analysis between 2018-2024 focused on patients aged 16+ with confirmed CRE infections in a hospital setting.
The findings highlight the urgent need for targeted infection control measures in immunocompromised patients, particularly those with organ transplants.

Alraddadi et al. (2025) studied this question.

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