Case report demonstrates improved diagnostic accuracy for splenic lesions using ultrasound and contrast-enhanced ultrasound, suggesting benefits for clinical evaluation.
Early diagnosis of splenic marginal zone lymphoma (SMZL) is difficult because of its insidious symptoms and slow progression. Combining conventional ultrasound with contrast-enhanced ultrasound can enable to differentiate between benign and malignant splenic lesions, which could guide further clinical examination and eventually improve the diagnostic rate of SMZL.
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Zhang et al. (2025) studied this question.
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