Extraosseous Ewing Sarcoma of the Scalp: A Rare Case Report

Background Extraosseous Ewing sarcomas account for approximately 20%–30% of all Ewing sarcomas. Among these, 5%–10% occur in the head and neck region, representing approximately 1%–3% of all Ewing sarcomas. Methods We report the case of a 33‐year‐old female patient with a progressively enlarging mass in the frontal scalp over the course of 18 months. The lesion had previously been surgically excised twice, with benign pathology reports on both occasions. Given the imaging findings suggestive of malignancy, a diagnostic surgical resection was performed. Results Histology and immunophenotyping were compatible with extraosseous Ewing sarcoma; therefore, adjuvant chemotherapy and radiotherapy were administered. Conclusions This represents the seventh reported case of primary involvement of the scalp; and the first reported in Latin America.