Randomized controlled trial improves NPPV adherence and quality of life in COPD patients, highlighting the impact of behavioral support.
This study aimed to analyze factors influencing home non-invasive positive pressure ventilation (NPPV) adherence in patients with chronic obstructive pulmonary disease (COPD), and to construct and evaluate the clinical effectiveness of a behavioral intervention program based on the Health Belief Model (HBM). The intervention program was developed through questionnaire surveys and semi-structured interviews with 200 patients, followed by Delphi expert consultations. Subsequently, a 3-month randomized controlled trial (RCT) was conducted to evaluate its efficacy, with the control group receiving conventional health guidance.Post-intervention, the intervention group demonstrated significantly higher total Health Belief Scale scores (4.2 ± 0.3 vs. 2.5 ± 0.4), improved NPPV behavioral adherence (32.4 ± 1.8 vs. 20.1 ± 2.5), and lower CAT scores (10.3 ± 2.1 vs. 20.5 ± 3.2) compared to the control group. Furthermore, blood gas analysis, 6-minute walk test results, and lung function indices were all significantly better in the intervention group (all P < 0.001). Behavioral intervention based on the Health Belief Model can effectively improve NPPV treatment adherence in stable COPD patients, enhance their quality of life, and improve physiological function, demonstrating significant clinical value for promotion.
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Tian et al. (2025) studied this question.
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