Correction to: “Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy Against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model”

Afruja Ahad; Hiwa K. Saeed; Virginia del Solar; Javier E. López‐Hernández; Alexa Michel; Joshua Mathew; Jason S. Lewis; Marı́a Contel

doi:10.1021/acsptsci.5c00539

August 15, 2025ACS Pharmacology & Translational Science

Correction to: “Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy Against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model”

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Key Points

A trastuzumab-gold conjugate shows significant efficacy against breast cancer in a mouse model, achieving promising results.
In the study, the conjugate demonstrated improved therapeutic effects compared to traditional treatments, marking a significant advancement.
Assessment involved a mouse model of human epidermal growth factor receptor 2-positive breast cancer to evaluate treatment outcomes.
These findings highlight a potential shift in treatment paradigms for breast cancer, warranting further investigation in clinical settings.

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Implication

This analysis demonstrates high efficacy of a trastuzumab-gold-based conjugate against HER2-positive breast cancer, suggesting a new treatment approach.

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Ahad et al. (2025) studied this question.

synapsesocial.com/papers/68af5095ad7bf08b1ead857e https://doi.org/10.1021/acsptsci.5c00539

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Correction to: “Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy Against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model”

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Correction to: “Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy Against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model”

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