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August 18, 2025Journal of Analytical Toxicology

Quantitation of alcohols and acetone in postmortem blood and urine using headspace gas chromatography mass spectrometry

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Authors

MEMonika EdstamSwedish National Board of Forensic MedicineGSGustav SundqvistSwedish National Board of Forensic MedicineRKRobert KronstrandLinköping University

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Implication

This analysis identifies alcohols in postmortem specimens, highlighting the role of mass spectrometry in detecting volatiles.

Key Points

  • The method improves detection of ethanol and acetone in postmortem blood and urine samples, enhancing toxicological analysis.
  • Validation confirmed that mass spectrometry accurately quantifies alcohols and other volatiles, ensuring reliable results.
  • Using isotope labeled internal standards reduced risks associated with previous identification methods in postmortem analysis.
  • The implementation of this method supports future studies on alcohol formation during decomposition, broadening toxicology diagnostics.

Cite This Study

Edstam et al. (2025) studied this question.

synapsesocial.com/papers/68af5231ad7bf08b1eada543https://doi.org/10.1093/jat/bkaf076
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