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Observational analysis shows improved nerve regeneration in a rat model of Bell's palsy with topical mitomycin-C, suggesting optimal decompression timing may enhance outcomes.
The timing of facial nerve (FN) decompression (FND) for Bell's palsy is controversial. Intraneural fibrosis is one of the factors affecting post-traumatic nerve regeneration. This study aimed to investigate the effects of decompression timing and antifibrotic agent topical mitomycin-C (MMC) on nerve regeneration in rats in which a Bell's palsy model was created.
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Çaytemel et al. (2025) studied this question.
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