Clinical study shows Shreshtanimbadi decoction improves symptoms of chronic sinusitis in 40 patients, indicating its potential benefits in Ayurveda.
Shirsha Shoola (Headache) is a very common condition of current society. Ayurveda Acharyas have been explained Shirsha Shoola as a type of Shiro Roga (diseases in the head). Kaphaja Shirsha Shoola is a common type of 07 Shirsha Shoola types. Kaphaja Shirsha Shoola occurs mainly due to vitiation of Kapha Dosha and Vata Dosha. With signs and symptoms, this condition can be correlated with chronic sinusitis. Shreshtanimbadi decoction consist of ten ingredients; Thriphala (Emblica officinalis, Terminalia bellirica, Terminalia chebula), Nimba Tvak (Azadirachta indica), Patola (Trichosanthes cucumerina L.), Megha (Cyperus rotundus), Rajini (Curcuma Longa), Thrayanthi (Baccopa Monneiri), Hema (Cassia angustifolia), and Amrita (Tinospora ordifolia). These herbs, which pacify vitiated Vata Dosha and Kapha Dosha to treat Kaphaja Shirsha Shoola. Forty selected patients were randomly divided into two groups of 20 for each treatment arm and controlled arm. The treatment group was treated with 120 ml of decoction of Shreshtanimbadi twice a day for 14 days. The second group was treated with 120 mL of placebo twice a day for 14 days. All patients were advised to follow Pathya (Wholesome food and behaviors). Assessment has been done before and after treatments. After treatment, treatments arm most of the patients’ symptoms were completely or partially relieved compared to controlled group (P < 0.001). Such as headache with76.91%, heaviness of the head from 87.9%, loss of appetite from 78.67%, peri-orbital edema from 73.20%, and ear itching from 70.00%. After the treatment, nine patients have been completely cured and all patients have been showed reduction of symptoms. It is observed that the Shreshta nimbadi decoction is beneficial for Kaphaja Shirsha Shoola (chronic sinusitis) Management.
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Rohini et al. (2025) studied this question.
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