Case report reveals chronic prostatitis as an extraintestinal manifestation of ulcerative colitis, highlighting inflammatory pathways.
Introduction Lower urinary tract symptoms are common in patients with inflammatory bowel disease; however, the association between ulcerative colitis and chronic prostatitis remains underrecognized. Case Presentation A 38‐year‐old man presented with frequent and painful urination unresponsive to the standard treatment of chronic prostatitis. He was subsequently diagnosed with ulcerative colitis based on persistent hematochezia and colonoscopy findings. Treatment with mesalamine and corticosteroids for ulcerative colitis led to improvements in both gastrointestinal and urinary symptoms. Conclusion This case suggests a possible link between chronic prostatitis and ulcerative colitis, indicating that prostatitis might represent an extraintestinal manifestation. This association might be explained by shared inflammatory pathways and the prostate's anatomical proximity to the rectum. Clinicians should consider inflammatory bowel disease in male patients exhibiting refractory chronic prostatitis and concurrent gastrointestinal symptoms.
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Sugihara et al. (2025) studied this question.
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