A Novel Particle Mass Calibration Strategy for the Quantification of AuNPs in Single Cancer Cells via Laser Ablation ICP-Mass Spectrometry. A case study

Antonio Bazo; Eduardo Bolea‐Fernandez; Kharmen Billimoria; Ana Rua-Ibarz; Maite Aramendía; Paula Menero Valdés; J. S. Morley; Silmara Neves; Armando Sánchez Cachero; Heidi Goenaga‐Infante; Martín Resano

doi:10.1039/d5ja00253b

January 1, 2025Journal of Analytical Atomic SpectrometryOpen Access

A Novel Particle Mass Calibration Strategy for the Quantification of AuNPs in Single Cancer Cells via Laser Ablation ICP-Mass Spectrometry. A case study

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Key Points

Quantification of AuNPs significantly improves in single cancer cells via novel calibration methods, ensuring better accuracy.
The calibration method revealed a more precise measurement of elemental content, enhancing the application scope.
Study implements laser ablation ICP-mass spectrometry for detailed investigation of individual cells.
This novel method may enable further advancements in cancer diagnostics and treatment analysis.

Implication

Novel particle mass calibration improves quantification of AuNPs in individual cancer cells, suggesting enhanced analytical capabilities.

Abstract

Laser ablation ICP-mass spectrometry (LA-ICP-MS) has developed as a powerful tool for elemental quantitative analysis of individual cells, assuring that the content of each cell is analyzed individually. However, this...

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Cite This Study

Bazo et al. (2025) studied this question.

synapsesocial.com/papers/68af540fad7bf08b1eadb2ca https://doi.org/10.1039/d5ja00253b

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A Novel Particle Mass Calibration Strategy for the Quantification of AuNPs in Single Cancer Cells via Laser Ablation ICP-Mass Spectrometry. A case study

Key Points

Implication

Abstract

Discussion

Cite This Study

A Novel Particle Mass Calibration Strategy for the Quantification of AuNPs in Single Cancer Cells via Laser Ablation ICP-Mass Spectrometry. A case study

Key Points

Implication

Abstract

Discussion

Cite This Study

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