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August 15, 2025Open Access

Supplementary Fig. S18 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer

Xianfeng Xu Caiwang Yan Lijun Bian Zhe Li Yuhui Yu Xia Zhu Yun Gao Hao Xu Fengyuan Li Yao Liu Ping Sun Zheng Wang Yao Fu Yue Jiang Juncheng Dai Hongxia Ma Zhibin Hu Hongbing Shen Gang Li Cheng Wang Guangfu Jin

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Key Points

Gastric cancer characteristics evolved alongside intestinal metaplasia, highlighting critical mutations.
Key findings show significant CNAs and mutation effects of APC and CDH1 on cancer development.
Assessment utilized genomic analyses to track changes in gastric cancer tissue over time.
This research may inform strategies for early detection and intervention in gastric cancer.

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Implication

Genomic analyses reveal characteristics of gastric cancer in intestinal metaplasia, indicating mutation impacts.

Abstract

CNAs and transcriptional impact of mutations in APC and CDH1.

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Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd15d https://doi.org/10.1158/0008-5472.29919186

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S8 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
2Supplementary Fig. S19 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
3Supplementary Fig. S14 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
4Supplementary Fig. S10 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
5Supplementary Fig. S11 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025

Supplementary Fig. S29 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S17 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S9 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025