Synergizing One Health with osteopathic medicine: toward a unified health approach (‘One HealthOM’)

The intersection of One Health—a collaborative, interdisciplinary approach addressing the interconnectedness of human, animal, and environmental health—and osteopathic medicine, which emphasizes holistic and preventive care, offers a promising but underdeveloped synergy for advancing public health. This perspective explores how doctors of osteopathic medicine (DOs), one of the fastest-growing segments of US healthcare professionals, can help operationalize One Health principles through education, research, and clinical engagement. Although osteopathic medical colleges have yet to fully institutionalize One Health frameworks, several emerging initiatives suggest a path forward. We highlight institutional examples that demonstrate how osteopathic training and philosophy can be leveraged to enhance disease prevention, biosurveillance, interdisciplinary research, and outreach in underserved communities. Rather than presenting a mature framework, this article offers a call to action: to more systematically integrate One Health into osteopathic medicine and to recognize the untapped potential of DOs as contributors to global health resilience.