Quantitative Biomechanical Profiling of Transformed Human Corneal Epithelial Cell

Indrianita Lionadi; Liam McLarnon; Gourav Bhattacharya; George A. Burke; Patrick Lemoine; Amir Farokh Payam

doi:10.1039/d5nr03190g

January 1, 2025NanoscaleOpen Access

Quantitative Biomechanical Profiling of Transformed Human Corneal Epithelial Cell

View Full Paper

Ask AI

Bookmark

Share

Key Points

Transformed human corneal epithelial cells exhibit distinct biomechanical profiles, influencing their function and behavior.
Key measures include cellular surface dynamics and viscoelastic properties impacting cell cycle progression.
Assessment utilized multimodal microscopy techniques including atomic force microscopy and force mapping for detailed insight.
Understanding these cellular dynamics may inform therapeutic strategies for corneal-related disorders and conditions.

Implication

Multimodal microscopy explores cell mechanics in human corneal epithelial cells, indicating vital cellular behavior changes.

Abstract

Cell mechanics, governed by cortical surface dynamics and cytoskeletal viscoelasticity, evolve throughout the cell cycle, influencing cellular function and behavior. Using multimodal microscopy—bimodal atomic force microscopy (AFM), force mapping, and...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Lionadi et al. (2025) studied this question.

synapsesocial.com/papers/68af59d2ad7bf08b1eade036 https://doi.org/10.1039/d5nr03190g

View Full Paper

Ask AI

Bookmark

Share

Quantitative Biomechanical Profiling of Transformed Human Corneal Epithelial Cell

Key Points

Implication

Abstract

Discussion

Cite This Study

Quantitative Biomechanical Profiling of Transformed Human Corneal Epithelial Cell

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading