Answers are grounded in this paper and cite their sources.
This research demonstrates the synthesis of 1,3-butadiynyl sulfide from thiols, highlighting its role in organic synthesis and materials science.
In this study, we aim to investigate base-free, direct electrophilic diynylation of thiols to 1,3-butadiynyl sulfide, a crucial structural motif in organic synthesis, chemical biology, and materials science using triisopropylsilyl diynyl benziodoxolone at room temperature. The resulting 1,3-butadiynyl sulfides were further derivatized to thiobitriazole via double azide–alkyne cycloaddition and to cyclobutene via [2+2] cycloaddition.
No takes yet. Share an insight, caveat, or question.
Tada et al. (2025) studied this question.
Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context: