Evaluation of macular and optic disc radial peripapillary vessel density with optical coherence tomography angiography in cases with iron deficiency anemia

August 18, 2025Benha Medical JournalOpen Access

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Key Points

Retinal microvascular changes due to iron deficiency anemia appear to be reversible with iron therapy, showing significant improvements in vessel density at follow-up.
Significant increases in hemoglobin and serum iron levels were observed following 3 months of iron treatment, indicating effective therapy.
Cross-sectional case-control study compared retinal vascular density in 24 individuals with iron deficiency anemia against 24 healthy controls.
Findings suggest optical coherence tomography may serve as a valuable tool for early detection of retinal ischemia in patients with iron deficiency anemia.

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Cross-sectional study evaluates retinal vascular density in iron deficiency anemia patients, suggesting OCTA detects ischemic changes.

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Ibrahim et al. (2025) studied this question.

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