August 26, 2025Bioinformatics AdvancesOpen Access

IGD: A simple, efficient genotype data format

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New genotype data format IGD shows over 100x speed and 3.5x size reduction, indicating enhanced efficiency for statistical genetics.

The IGD file format improves data processing speed significantly, achieving over 100 times faster performance than vcf.gz.
This novel format also reduces file size, demonstrating a 3.5 times reduction on biobank-scale whole-genome sequence data.
Implementation of IGD in Python consists of fewer than 350 lines of code, reflecting its simplicity and efficiency.
Availability includes a C++ library for IGD and tools to convert existing vcf.gz files, enhancing usability in research.

DeHaas et al. (2025) studied this question.

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