Highlights from Issue 3, 2025: Reflections on Leadership, Innovation, and Rare Diagnoses

Welcome to the third issue of 2025. This issue is a fairly small one. We have a review, four original articles, a pathology corner piece, and three case reports. We have a professional review on becoming a successful chief medical officer (CMO). It is a quick primer revisiting critical issues needed by those who aspire to become CMOs, often called medical directors. Many senior clinicians may mistakenly believe that their rise to a medical director position is a recognition of their clinical excellence. The primer revisited the skills, qualifications, and attributes needed to become a successful CMO.