Formulation of mouth disintegrating tablets enhanced drug release in vitro, suggesting improved patient compliance with efficient treatment.
This study developed and evaluated mouth disintegrating tablets (MDTs) of Empagliflozin to enhance patient compliance and rapid drug onset. Using UV spectrophotometry (λmax 225nm in 0.1NHCl), MDTs were prepared via direct compression with superdisintegrants SSG, Crospovidone, and Croscarmellose sodium. All formulations met pharmacopeial standards. Batch F-6 with Crospovidone showed the best performance, releasing 99% of the drug within 30 minutes. The findings confirm the effectiveness of a minimal-excipient, direct compression method for efficient Empagliflozin delivery.
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Shilpa et al. (2025) studied this question.
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