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Research shows S protein cleavage preserves formulation potency and antitumor activity of cowpea mosaic virus, suggesting therapeutic potential.
As cowpea mosaic virus (CPMV) advances as a candidate for intratumoral immunotherapy, we have found that cleavage of a sequence from its small (S) coat protein does not impair the formulation potency and antitumor activity.
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Simms et al. (2025) studied this question.
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