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August 26, 2025Bioscientia Medicina Journal of Biomedicine and Translational ResearchOpen Access

The Lethal Nexus: Sarcopenic Obesity and the Prospective Risk of All-Cause and Cardiovascular Mortality in Older Adults-A Systematic Review and Meta-Analysis of Longitudinal Cohort Studies

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Authors

MAMuhammad Ridho AzhariRMRoza Mulyana

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Overview

Systematic review reveals sarcopenic obesity increases all-cause and cardiovascular mortality risks in older adults, suggesting urgent intervention needs.

Key Points

  • Sarcopenic obesity is linked to a significantly increased risk of all-cause mortality, with a pooled hazard ratio of 1.58.
  • Analysis included 8 longitudinal cohort studies involving 45,280 older adults with an average follow-up of 8.2 years.
  • The study identifies cardiovascular mortality risk as even more pronounced, with a pooled hazard ratio of 1.75.
  • Findings emphasize the importance of early detection and treatment for sarcopenic obesity in aging populations.

Cite This Study

Azhari et al. (2025) studied this question.

synapsesocial.com/papers/68af63e9ad7bf08b1eae462bhttps://doi.org/10.37275/bsm.v9i11.1431
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