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August 25, 2025PlantsOpen Access

In Vivo Investigation of Cardioprotective Effects of Melilotus officinalis and Melilotus albus Aerial Parts Extracts for Potential Therapeutic Application

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Authors

ATAnca ToiuAVAna-Maria VlaseLVLaurian Vlase

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Overview

In vivo analysis shows antioxidant properties of Melilotus extracts improve cardiac health, indicating potential for treatment.

Key Points

  • Melilotus officinalis and Melilotus albus extracts significantly reduce oxidative stress markers and improve cardiac function.
  • Pretreatment with M. officinalis increased total thiols, which are important for heart health, and reduced nitric oxide levels when using M. albus.
  • The study identifies key polyphenolic compounds in extracts, such as catechin and chlorogenic acid, which contribute to their antioxidant activity.
  • Evaluation methods included ECG monitoring and serum markers to assess the extracts' effects on myocardial ischemia.

Cite This Study

Toiu et al. (2025) studied this question.

synapsesocial.com/papers/68af63e9ad7bf08b1eae47dbhttps://doi.org/10.3390/plants14172639
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