Background and objective: The esophageal cancer was considered as the eighth common type of cancer as well as the sixth cause of mortality across the world according to the report of International Agency of Research. The current study was aimed to evaluate the epidemiology, incidence, and mortality rates of esophageal cancer in Iran compared to other regions of the world. Methods and materials: In the current study, the incidence and mortality rates of all cancers were extracted on behalf of the Global Cancer Project in 2012. Results: In 2012, some 456000 new cases (3.2% of the overall) of esophageal cancer as well as 400000 cases of cancer-related mortality were registered. The incidence rates in the male (323008 cases, 4.4 cases per 100000 people) were higher than that in females (132776 cases, 2 cases per 100000 people). The incidence rate of cancer in Iran was estimated as 6.3 cases per 100000 people highlighted as the two-folds of the universal incidence rate (6.3 cases compared to 3.2 cases per 100000 people). Also, the incidence rate of esophageal cancer in Iran was higher than other regions of the world. The global rate of esophageal cancer mortality was estimated as 400169 cases (5 cases per 100000 people). The mortality rate of esophageal cancer in Iran was indicated as 7.8 cases per 100000 people highlighting the more mortality rate of esophageal cancer in Iran compared to other regions of the world. Conclusion: As for the higher incidence and mortality rates of esophageal cancer in Iran compared to other regions of the world, it is suggested to perform the studies so as to evaluate the related-risk factors in order to decline the incidence rate of the disease.
Khazaei et al. (2019) studied this question.