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September 5, 2025ACS Applied Materials & Interfaces

Designing Protein-Based Nanoparticles for Therapeutic Applications

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Authors

JCJian CuiKWKeqing WangZWZheyu Wu

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Overview

Review highlights design strategies and clinical challenges of protein-based nanoparticles, indicating their versatile applications.

Key Points

  • Protein-based nanoparticles offer advantages like biocompatibility and biodegradable properties for drug delivery, making them promising alternatives in medicine.
  • In-depth analysis of recent studies reveals that design strategies such as surface modification and stimuli-responsive engineering can improve therapeutic outcomes.
  • Key challenges affecting clinical translation include stability and immunogenicity, which need to be addressed to enhance the applicability of protein nanoparticles.
  • Emerging technologies in gene editing and protein-based therapies may significantly facilitate the development of next-generation protein-based nanoparticle solutions.

Cite This Study

Cui et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a352b87ece8dc954d7dhttps://doi.org/10.1021/acsami.5c10918
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