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September 5, 2025Clinical review for general practice0 citationsOpen Access

Endometrial Role in Pregnancy Loss: Immunohistochemical and Clinical Insights

The role of the endometrium in the pathogenesis of pregnancy loss: immunohistochemical and clinical aspects

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Authors

GMGulnara D. MatrizaevaGIGulchekhra A. IkhtiyarovaNDNigora K. Dustova

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Overview

Observational study finds hormonal and immunological factors influence pregnancy loss in women, indicating potential for improved diagnostics.

Key Points

  • Increased antibodies to chorionic gonadotropin were found in women with habitual miscarriage.
  • A significant correlation was observed between the Ki-67 index and stromal cell differentiation in normal pregnancies.
  • Estrogen receptor expression in the main group was reduced by 2.1 times compared to healthy women.
  • Dysregulation of hormones and their receptors can lead to unsuccessful implantation and miscarriage.

Cite This Study

Matrizaeva et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a3d2b87ece8dc9550c3https://doi.org/10.47407/kr2025.6.2.00566
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