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September 5, 2025Biomaterials ScienceOpen Access

Biomaterials and stem cells targeting the microenvironment for traumatic brain injury repair: progress and prospects

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Authors

YGYating GaoZTZhijian TangZWZitao Wu

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Overview

This review explores how biomaterials and stem cells improve recovery from traumatic brain injury, highlighting the importance of the microenvironment.

Key Points

  • Integrated therapies using biomaterials and stem cells promote recovery from traumatic brain injury by addressing the microenvironment.
  • The review details developments in using hydrogels and nanofiber scaffolds for enhancing neural regeneration and vascularization.
  • Stem cells can improve outcomes by secreting beneficial factors and differentiating into neural cells, while biomaterials provide critical support.
  • These combinatorial approaches underline the need for tailored strategies to effectively tackle the complex environment of traumatic brain injury.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a492b87ece8dc955832https://doi.org/10.1039/d4bm01521e
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