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September 5, 2025Journal of Clinical MedicineOpen Access

The Long-Term Efficacy of Cephalosporin in Elderly Hip Fracture Patients: A Comprehensive Analysis

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Authors

HPHuiqing PanTongji University XWXiao WangYuhuangding Hospital QOQingjian OuTongji University

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Implication

Observational analysis reveals reduced mortality risk with cephalosporin monotherapy in elderly hip fracture patients, suggesting advantages for certain subgroups.

Key Points

Monotherapy with cephalosporin showed a 54% lower mortality risk compared to combination therapy at one year.
Cox proportional hazards models indicated significant differences in mortality rates with 28-day HR of 0.46, 90-day HR of 0.60, and 180-day HR of 0.67.
Subgroup analyses revealed that males and those with high comorbidity (CCI ≥ 5) benefited most from cephalosporin monotherapy.
Patients with osteoporosis experienced unique advantages, highlighting the importance of tailored antibiotic therapy for better outcomes.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/68bb3efd2b87ece8dc957b4a https://doi.org/10.3390/jcm14176086

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Implication

Observational analysis reveals reduced mortality risk with cephalosporin monotherapy in elderly hip fracture patients, suggesting advantages for certain subgroups.

The Long-Term Efficacy of Cephalosporin in Elderly Hip Fracture Patients: A Comprehensive Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

The Long-Term Efficacy of Cephalosporin in Elderly Hip Fracture Patients: A Comprehensive Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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