Clinical Interventions for Depression and Anxiety in Mothers of Children with Autism Spectrum Disorder in China

Mothers of children with autism spectrum disorder (ASD) in China often experience elevated levels of depression and anxiety, which can adversely affect both the mothers’ well-being and their children’s developmental outcomes. This review addresses the urgent need to support these mothers by examining current clinical intervention strategies for maternal depression and anxiety in the context of raising a child with ASD in China. We conducted a comprehensive literature search (2022–2025) of international and Chinese studies, including randomized trials, meta-analyses, and program evaluations, to identify effective interventions and emerging practices. The findings reveal that a range of interventions can substantially alleviate maternal psychological distress. Psychotherapeutic approaches—particularly cognitive-behavioral therapy (CBT) and mindfulness-based programs—consistently reduce parental stress and, when appropriately targeted, depressive symptoms. Behavioral and skills-training programs (such as parent-mediated ASD interventions) not only improve child behavior but also indirectly reduce mothers’ stress by empowering them with effective parenting techniques. Family support and psychoeducational interventions (including peer support groups and parenting workshops) help combat isolation and increase coping self-efficacy, leading to improvements in mood and anxiety. Pharmacological treatment (e.g., SSRIs for depression/anxiety) remains an important option for moderate-to-severe cases, and early evidence suggests that integrating mental health services into pediatric ASD care (through technology and multidisciplinary teams) can improve access and outcomes. In conclusion, addressing the mental health of mothers caring for children with ASD is a public health priority in China. Multiple evidence-based interventions—when tailored to cultural norms and delivered in accessible formats—can significantly reduce maternal depression and anxiety. Such improvements benefit not only the mothers, but also their children’s progress and the overall wellness of ASD families.