A Complex Case of Knee Osteoarthritis Associated with Synovial Chondromatosis, Gout, and Hypothyroidism: A Multimodal Management Approach

This case report presents a 40-year-old male patient, Mr. Mizan, who attended Upasham Health Point, Baridhara, Dhaka, Bangladesh, on December 1st, 2024, with complaints of left knee joint pain and swelling accompanied by a persistent cough. His diagnostic investigations revealed a multifactorial pathology involving osteoarthritis (OA) with secondary synovial chondromatosis, elevated serum uric acid levels suggestive of gout, and thyroid function abnormalities consistent with hypothyroidism. The patient's condition was managed through a comprehensive regimen comprising febuxostat, corticosteroids, NSAIDs, muscle relaxants, supplements, and supportive therapy. Serial laboratory evaluations demonstrated improvement in biochemical markers and symptom relief. This report underscores the importance of multimodal diagnostic and therapeutic strategies in managing complex joint pathologies, especially in resource-limited settings.