Retrospective analysis identifies challenges in managing obstructive nephropathy due to tumors, suggesting improved early diagnosis and treatment options.
This is a retrospective study covering a period from January 2020 to December 2022, the main objective of which was to identify the problems of management of tumor-related obstructive nephropathy at the Luxembourg University Hospital. We included 79 patients from 240 cancer cases. The hospital admission rate was 32.91%, the mean age was 56.37 years, ranging from 19 to 82 years; the sex ratio was 0.83, favoring women. Cervical cancer was the most common type (32.9%). The usual reason for consultation was elevated serum creatinine (73.4%); deterioration in general condition and pain were the main clinical signs (50.6%). Anemia (42%) and ionic disorders such as metabolic acidosis (19%) were frequently encountered; CT scan was systematically performed in all patients in our study; Palliative surgery and chemotherapy were performed in 70.88% and 68.35%, respectively; Obstacle removal was observed in 22.8% of patients in our study; Hemodialysis was performed in 67% of patients and 49.05% of these 67% were receiving chemotherapy. The prognosis under hemodialysis was poor with 39.24% deaths and 15.18% stability. The main causes of these deaths are late diagnosis, insufficient technical facilities and lack of knowledge of cancer by the population.
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Bilumbu et al. (2025) studied this question.
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