Cholecystectomy effect on the digestive system

Cholecystectomy continues to be the main method of treating gallstone disease. This is one of the most frequent surgical procedures in the world. Despite the continuous improvement of techniques and good surgical results, the consequences of cholecystectomy for the physiology of the gastrointestinal tract and metabolism in general can be unfavorable. In the absence of a gallbladder, the mechanics of digestion change, which affects the condition of the digestive tube, hepatobiliary system, and pancreas. In addition, without a gallbladder, the body suffers from the modulation of the flow of bile acids, which normally should compensate for the metabolic stress caused by eating. The article highlights the most important aspects of the effect of cholecystectomy on the gastrointestinal tract, the mechanisms of these effects and the results of modern research on these issues.