Phytochemistry and pharmacology of Pandanus amaryllfolius Roxb.

Background: An interesting medicinal plant in Southeast Asia, Pandanus amaryllifolius Roxb. (P. amaryllifolius) is used as a flavouring and in Southeast Asian folk medicine to treat a range of illnesses. Objective: An overview of research on the phytochemistry and pharmacological effects of P. amaryllifolius is the goal of this paper. Method: This review was based on an analysis of scientific literature sourced from various electronic databases, including PubMed, ScienceDirect, Google Scholar, Web of Science, and Scopus. Result: Pandamarilactonine-A and -B, pandanamine, pandamarilactone-1, and pandamarilactone-32 are among the primary chemical compounds extracted and identified from P. amaryllifolius. Norpandamarilactonines C and D, pandalizine C, pandalizine D, pandalizine E, pandanusine A, pandanusine B, and pandamarilactone-3. The potential pharmacological effects of P. amaryllifolius include hepatoprotective, antiviral, anticancer, antibacterial, and antihyperglycemic effects in the context of metabolic syndrome. Conclusion: P. amaryllifolius may be used to treat various diseases; however, insufficient studies have been conducted on the phytochemistry of the plant. As a result, more research should concentrate on drug development, P. amaryllifolius leaf toxicity testing, and the isolation and identification of active compounds.