Supplemental Figure S4 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Melanie K. Flores; Jessica L. Janes; Mirajul Islam; Junxiang Wan; Jiali Liu; Romonia R. Reams; Li‐Ming Su; Kelvin Yen; Hemal H. Mehta; Allison Reagan; Lauren E. Howard; Emily Wiggins; Adriana C. Vidal; Stephen J. Freedland; Pinchas Cohen

doi:10.1158/1940-6207.30028912

September 2, 2025Open Access

Supplemental Figure S4 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

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Key Points

Mitochondrial DNA copy number is a powerful predictor of prostate cancer in White individuals.
Significant differences in mitochondrial DNA distribution were observed between Black and White individuals.
This analysis involved the assessment of plasma and white blood cell (WBC) mitochondrial DNA levels.
Findings suggest racial disparities in mitochondrial DNA copy number with implications for prostate cancer risk.

Implication

Comparison of mitochondrial DNA levels in Black and White individuals reveals race-based predictors of prostate cancer.

Abstract

Supplemental Figure S4 shows a comparison of the distribution of Mitochondrial DNA copy number by prostate cancer grade for Black and White Individuals stratified by plasma and WBC.

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Cite This Study

Flores et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd028d9 https://doi.org/10.1158/1940-6207.30028912

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Supplemental Figure S4 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Figure S4 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

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