Observational analysis reveals formation of N-iodonium-iminoiodinane as key N-atom transfer agent, suggesting new pathways for oxidative amination reactions.
Key Points
Formation of N-iodonium-iminoiodinane governs the rate of oxidative aminative cleavage, highlighting its role as a key intermediate.
In situ studies reveal that the N-iodonium-iminoiodinane, not iodonitrene, functions as the primary N-atom transfer agent.
Kinetic analysis using various methods, including H/D and 12C/13C KIE, supports the electrophilic nature of the N-iodonium-iminoiodinane.
Findings enhance understanding of hypervalent iodine's role in N-atom transfer, potentially guiding future reagent development.