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Supplementary figure analyzes gut microbiota's role in CAR-T therapy outcomes in myeloma patients, highlighting significant diversity metrics.
Supplementary Figure S14 examines the pre-CAR T-cell infusion gut microbiota taxonomic profiles based on the patients' hospital of origin. This figure includes a principal component analysis (PCA) plot showing gut microbiota composition by hospital, arrows indicating the influence of variables on patient separation, the Reciprocal Simpson diversity index of the gut microbiome, and a stacked bar plot of mean relative abundance of bacterial families across different clinical trial sites.
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Uribe‐Herranz et al. (2025) studied this question.
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