Case report highlights left atrial mass causing chest pain in a woman with choriocarcinoma, suggesting new diagnostic approaches.
Cardiac metastases from choriocarcinoma are exceptionally rare, with only 11 cases reported in the literature to date. Here we present the case of a 37-year-old woman with progressively worsening exercise intolerance, chest pain, and occasional hemoptysis after childbirth. Initial chest computed tomography revealed a pulmonary mass and a left atrial mass extending from the right inferior pulmonary vein. Blood test results raised suspicion of a gestational choriocarcinoma. The patient is responding to chemotherapy and is currently asymptomatic. Most previously reported cases were diagnosed postmortem, emphasizing the diagnostic challenges of this condition and the rarity of our case. Choriocarcinoma should be considered as a potential differential diagnosis for intracavitary cardiac masses in young women, especially when involving the left atrium.
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Barcía et al. (2025) studied this question.
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