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September 10, 2025PLoS neglected tropical diseases0 citationsOpen Access

Morbidity and Schistosoma Mansoni Infection Intensity in Uganda

The relationship between expelled eggs, morbidity and age in a Schistosoma mansoni endemic setting in Uganda: Implications for current elimination policies

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Authors

RLRivka LimRLRuhi LahotiJCJessica Clark

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Overview

Observational analysis reveals age predicts morbidity in Schistosoma mansoni endemic regions, highlighting current policy gaps.

Key Points

  • Age was a consistent predictor of morbidity, with pre-school-aged children showing the highest burden of conditions.
  • Prevalence of liver parenchyma image pattern and portal vein dilation was observed at 9% and 34%, respectively.
  • Current infection intensity metrics may be inadequate for assessing schistosomiasis morbidity, urging policy re-evaluation.
  • Positive malaria status correlated with both portal vein dilation and anaemia, emphasizing co-infection effects.
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Cite This Study

Lim et al. (2025) studied this question.

synapsesocial.com/papers/68c188579b7b07f3a0612418https://doi.org/10.1371/journal.pntd.0012750
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