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Observational analysis highlights non-invasive diagnosis of portal hypertension and esophageal varices in NAFLD, suggesting potential improvements in patient care.
Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern, affecting approximately25% of adults worldwide (WHO). The disease spectrum ranges from simple steatosis to non-alcoholicsteatohepatitis (NASH), which can progress to fibrosis, cirrhosis, and liver cancer. Complications such asportal hypertension and esophageal varices pose diagnostic challenges due to the limitations of traditionalinvasive methods like hepatic venous pressure gradient (HVPG) measurement and endoscopy, which arecostly, not widely accessible, and carry inherent risks.
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Shanka et al. (2025) studied this question.
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