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September 4, 2025Open Access

Supplementary Figures S1-S9 from Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets

Vindhya Vijay Negin Karisani Lei Shi Yu-Han Hung Phuong Vu Prabhat Kattel Lauren Kenney Joshua Merritt Ramzi Adil Qibiao Wu Yuanli Zhen Robert Morris Johannes Kreuzer Meena Kathiresan Xcanda Ixchel Herrera Lopez Haley Ellis Ilaria Gritti Lilian Lecorgne Ines Farag Alexandra Popa William Shen Hiroyuki Kato Qin Xu Eranga R. Balasooriya Meng‐Ju Wu Jinkai Wan Hiroshi Kondo Saireudee Chaturantabut Srivatsan Raghavan Matthew D. Hall Samarjit Patnaik Min Shen Robin Kate Kelley James M. Cleary Michael S. Lawrence David E. Root Krushna C. Patra Vanessa S. Silveira Cyril H. Benes Vikram Deshpande Dejan Juric William R. Sellers Cristina R. Ferrone Wilhelm Haas Francisca Vázquez Gad Getz Nabeel Bardeesy

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Key Points

The analysis identifies distinct molecular subtypes of biliary tract cancer, and may guide future therapeutic strategies.
Key evidence includes the identification of multiple therapeutic targets, underscoring varied treatment potentials.
Assessment using supplementary figures from an atlas provides insights into the cancer's biological diversity and complexity.
Implications point to the necessity for tailored therapeutic approaches based on the identified subtypes and targets.

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Implication

Analysis reveals molecular subtypes and therapeutic targets in biliary tract cancer, highlighting potential treatment avenues.

Abstract

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Cite This Study

Vijay et al. (2025) studied this question.

synapsesocial.com/papers/68c18c089b7b07f3a06148c3 https://doi.org/10.1158/2159-8290.30050676

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1Data from Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets2025
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