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September 10, 2025Bangladesh Journal of Pharmacology0 citationsOpen Access

Cytotoxic Effects of Luffa Cylindrica Leaf Extract on MCF-7 Cell Lines

Cytotoxic effect of Luffa cylindrica leaf extract on MCF-7 cell lines

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Authors

HAHassan ArshadMSMohammad Saleem

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Overview

Investigation reveals Luffa cylindrica reduces MCF-7 cell viability and ROS levels, indicating potential in breast cancer treatment.

Key Points

  • Luffa cylindrica leaf extract significantly reduced MCF-7 cell viability, showing potential effectiveness against breast cancer.
  • The study demonstrated a dose-dependent cytotoxic effect with p<0.05, suggesting meaningful results in cell viability reduction.
  • Morphological analysis confirmed that Luffa cylindrica induces apoptotic cell death in MCF-7 cells, enhancing its therapeutic potential.
  • The extract effectively reduced reactive oxygen species and delayed migration, highlighting its anti-metastatic properties.
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Cite This Study

Arshad et al. (2025) studied this question.

synapsesocial.com/papers/68c18f329b7b07f3a0615876https://doi.org/10.3329/bjp.v20i3.81752
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