Current and Future Trends in Cancer Mortality in Hungary: An Analysis of 2022 GLOBOCAN Estimates and Projections to 2050

Abstract Objective Hungary continues to have one of the highest cancer mortality rates in Europe, along with persistent gender disparities. This study offers an updated analysis of cancer mortality patterns in 2022 and projects future trends through 2050, aiming to support targeted public health strategies. Design This study examined cancer mortality in Hungary by utilising the 2022 estimates from the Global Cancer Observatory (GCO). We extracted and analysed age-standardised mortality rates (ASMRs) and cumulative risks, categorised by sex and cancer type. We also conducted comparisons with the European average and reviewed projections of cancer deaths through 2050 to evaluate future trends. Results In 2022, Hungary recorded 32,482 cancer-related fatalities, with a greater incidence in males (ASMR: 187.9 per 100,000) compared to females (ASMR: 112.2). Lung cancer continued to be the leading cause of cancer deaths for both genders, showing an ASMR of 39.8 per 100,000. Significant contributors also included colorectal, pancreatic, prostate, and breast cancers. Projections for 2050 suggest a 32.4% rise in cancer deaths among males and a 10% increase among females. The disparity in cancer mortality rates by gender is anticipated to expand, especially for lung and liver cancers. Conclusions Cancer mortality rates in Hungary continue to be notably high, particularly among men. The anticipated increase in deaths by 2050 highlights the pressing need for enhanced prevention, early detection, and fair access to quality care. Gender-sensitive, data-driven public health strategies are essential for decreasing preventable cancer deaths and tackling ongoing disparities.