Study protocol evaluates nitric oxide's effects on hemodynamics in patients with pulmonary hypertension, indicating potential therapies for mitigating elevated pressures.
Background: Elevated pulmonary arterial pressure (PAP) is associated with poor prognosis in patients with functional mitral regurgitation (MR) undergoing transcatheter mitral valve repair (TMVr). Nitric oxide (NO) inhalation therapy reduces PAP and pulmonary vascular resistance (PVR) after open-heart surgery, but its efficacy in patients with pulmonary hypertension (PH) undergoing catheter intervention remains unclear.
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Tani et al. (2025) studied this question.
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