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September 5, 2025Molecular CancerOpen Access

Retraction Note: Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

Jianan Chen Yan Yu Hua Li Qiuyue Hu Xiaolong Chen Yuting He Chen Xue Fang Ren Zhigang Ren Juan Li Liwen Liu Zhenfeng Duan Guangying Cui Ranran Sun

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Key Points

Long non-coding RNA PVT1 is implicated in promoting tumor progression in gallbladder cancer.
The study suggests that PVT1 regulates the miR-143/HK2 axis, crucial for tumor growth dynamics.
The article has been retracted, indicating potential issues with the findings or methodologies.
Further investigations may explore alternative pathways impacting gallbladder cancer progression.

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Implication

Retraction notice highlighting how long non-coding RNA PVT1 regulates the miR-143/HK2 axis in gallbladder cancer.

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Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c193de9b7b07f3a061773d https://doi.org/10.1186/s12943-025-02452-1

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Downregulation of Long Noncoding RNA TUG1 Inhibits Proliferation and Induces Apoptosis Through the TUG1/miR-142/ZEB2 Axis in Bladder Cancer Cells [Retraction]Review · 2026
2Retracted: Long Non-Coding RNA Plasmacytoma Variant Translocation 1 (PVT1) Enhances Proliferation, Migration, and Epithelial-Mesenchymal Transition (EMT) of Pituitary Adenoma Cells by Activating β-Catenin, c-Myc, and Cyclin D1 Expression2024
3Retraction Note: Long noncoding RNA MNX1-AS1 overexpression promotes the invasion and metastasis of gastric cancer through repressing CDKN1A.2025
4<scp>RETRACTION</scp>: Silencing Circular <scp>RNA VANGL1</scp> Inhibits Progression of Bladder Cancer by Regulating <scp>miR</scp>‐1184/<scp>IGFBP2</scp> Axis2025
5Retraction: MicroRNA-221-3p Plays an Oncogenic Role in Gastric Carcinoma by Inhibiting PTEN Expression2025

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<scp>RETRACTION</scp>: <scp>LncRNA SNHG14</scp> Contributes to the Progression of <scp>NSCLC</scp> Through <scp>miR</scp>‐206/<scp>G6PD</scp> Pathway2025
Nodal Regulates Bladder Cancer Cell Migration and Invasion via the ALK/Smad Signaling Pathway [Retraction]2026
RETRACTION: lncRNA PDCD4‐AS1 Promotes the Progression of Glioma by Regulating miR‐30b‐3p/METTL7B Signaling2025

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