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This analysis identifies collagen turnover biomarkers in gastric cancer, suggesting their potential in non-invasive prediction of patient outcomes.
Background: The tumor stroma plays a pivotal role in gastric cancers (GC). Circulating collagen turnover markers of type I collagen (reC1M), type III collagen (PRO-C3 and C3M), type IV collagen (C4G), type VIII collagen (PRO-C8 and TUM), type XI collagen (PRO-C11) and type XVII collagen (PRO-C17) may be used as potential non-invasive biomarkers.
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Kaps et al. (2025) studied this question.
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