Systematic review evaluates triamcinolone's effects on postoperative edema and fibrosis in rhinoplasty, suggesting improved patient outcomes.
Introduction Postoperative edema and fibrosis are key concerns following rhinoplasty, affecting outcomes and patient satisfaction. Triamcinolone acetonide (TA) is used for its proven anti-inflammatory and anti-fibrotic effects. Objective This study aims to evaluate the efficacy, usage profile, and safety of TA injections after rhinoplasty, focusing on postoperative edema and supratip fullness. Material and Methods A systematic review was conducted via PubMed and the Cochrane Database to identify studies on corticosteroid injections after rhinoplasty, following PRISMA guidelines and predefined selection criteria. Results Nine studies were included in the analysis. These studies focused on the postoperative use of TA after rhinoplasty and assessed their impact on key outcomes such as edema reduction, fibrosis control, and the improvement of supratip fullness following rhinoplasty. Discussion TA injections were consistently associated with a significant reduction in postoperative edema and the incidence of pollybeak deformities. Current evidence supports the subcutaneous administration of TA at a 10 mg/mL concentration, initiated no earlier than 4 weeks following rhinoplasty. Injections are typically delivered at 4 to 6 week intervals, with a maximum volume of 0.3 mL per session, for a total of 2 to 4 administrations, depending on clinical response. TA showed a consistent safety profile with mild and infrequent side effects. Effects appeared within 7–14 days and lasted about 4 to 6 weeks. Conclusion TA is an effective adjunct in the postoperative management of rhinoplasty, particularly in patients with thick or reactive soft-tissue envelopes. Standardized, personalized protocols are needed, along with better studies and objective outcome tools.
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Villarroel et al. (2025) studied this question.
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