Dysthyroidism in Chronic Hemodialysis Patients

Objective: The purpose of this study is to investigate the thyroid profile in HDC in order to determine prevalence and incidence, and to identify factors favouring each thyroid disorder. Methods: This is a retrospective study spread over an 8-month period from January to August 2024, based on the exploitation of hospital records of adult patients on chronic hemodialysis. Biological results were collated from computerized data from the Biochemistry Laboratory. Results: Nearly 36% of patients presented with anemia.Phosphocalcic disorders were dominated by hyperparathyroidism, mean calcemia 89.25 mg/l , mean phosphoremia 37.3 mg/l with high PAL . CRP varied between 0 and 60mg/l. TSH varied between 0.01 and 10.8 mIU/L. Hormone assays revealed hypothyroidism in 15 patients, representing an estimated prevalence of 25%. FT3 was low in 11 patients, with a mean of 1 ± 0.26 ng/l. 3 patients had both low FT3 and low FT4, with a mean FT4 of 0.5 ± 1 ng/l. 1 hemodialysis patient had a very high TSHus (TSHus = 11mUI/l). Conclusion: Inflammatory syndrome, nutritional status, advanced age and long duration of hemodialysis are risk factors for dysthyroidism. Systematic screening for thyroid disorders in HDC patients should be carried out by means of biological tests (TSHus,T3L,T4L), and strict annual follow-up is essential.