Prospective analysis reveals 93.2% clinical-radiological and 84.7% clinical-histopathological concordance in sinonasal masses, highlighting the role of imaging and histopathology.
Aim: To correlate the clinical findings, radiological findings of various sinonasal masses in patients along with histopathological diagnosis. Material And Method: The study was a prospective cross-sectional analysis of 59patients with sinonasal masses conducted over 18months at NIMS&Research, Jaipur. Inclusion required informed consent and prior diagnosis of nasal mass, while cases with other nasal pathologies or unfit for procedures were excluded. Diagnosis and evaluation were done through clinical exams, imaging(X-ray, CT/MRI), nasal endoscopy, FNAC, and biopsy. Results: The 18month study at NIMS&Research, Jaipur, included 59patients with sinonasal masses, mostly males aged 19–30, with nasal obstruction being the most common symptom. Diagnostic tools revealed varying patterns of nasal and sinus involvement, with bilateral sinonasal polyposis being the most frequent finding across clinical, radiological, and histopathological evaluations. High correlation was observed between clinical, radiological, and histopathological diagnoses, with 93.2%clinical-radiological and 84.7%clinical-histopathological concordance. Conclusion: The study highlights the need for a multidisciplinary approach—combining clinical evaluation, imaging(CT/MRI), and histopathology—for accurate diagnosis and treatment of sinonasal masses. It emphasizes histopathology as the gold standard and advocates for larger, multicenter studies to strengthen findings.
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Rathi et al. (2025) studied this question.
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