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This review analyzes efficacy and side effects of anticonvulsants, highlighting pharmacoeconomic factors in treatment strategies.
This article reviews efficacy, side effects, impact on quality of life, pharmacoeconomic parameters of аnticonvulsants across different generations. It compares first-, second-, and third-generation drugs, analyzing their advantages and disadvantages in terms of cost, side effects and efficacy. Special attention is given to strategies for minimizing side effects, including pharmacogenetic testing, dose optimization, and therapeutic monitoring. The combined therapy with levetiracetam and lacosamide for refractory epilepsy is discussed.
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Goransky et al. (2025) studied this question.
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