Investigation of the relationship of lysyl oxidases on neck metastasis and prognosis in early stage oral cavity cancers.

Vahdettin Emre Şahin; Kerem Öztürk; Göksel Turhal; Alı Veral

doi:10.19161/etd.1622224

September 8, 2025Ege Tıp DergisiOpen Access

Investigation of the relationship of lysyl oxidases on neck metastasis and prognosis in early stage oral cavity cancers.

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Key Points

LOX and LOXL-2 expression correlates with neck metastasis in early-stage tongue cancer patients, revealing important prognostic indicators.
In a cohort of 43 patients, 37.2% exhibited LOX expression, while 34.8% showed LOXL-2 expression, highlighting their relevance to metastasis.
Analysis indicates that higher LOX expression is associated with T1 tumors and positive lymph node status, emphasizing its role in disease progression.
Further research is needed to understand LOX and LOXL-2 as therapeutic targets in head and neck cancers.

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Implication

This investigation reveals effects of lysyl oxidases on neck metastasis and prognosis in young adults with tongue cancer, suggesting potential clinical implications.

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Şahin et al. (2025) studied this question.

synapsesocial.com/papers/68c199da9b7b07f3a061aec6 https://doi.org/10.19161/etd.1622224

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Investigation of the relationship of lysyl oxidases on neck metastasis and prognosis in early stage oral cavity cancers.

Key Points

No abstract yet

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Implication

Discussion

Cite This Study

Investigation of the relationship of lysyl oxidases on neck metastasis and prognosis in early stage oral cavity cancers.

Key Points

No abstract yet

Ask about this paper

Implication

Discussion

Cite This Study

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